А вот про "Янтавит" ничего там не пишется. Наверно, это из какой-то "другой оперы"

вот ведь и подпись есть, а все равно ничего не понятно
"Figure 1 | Inhibition of cyst epithelial cell Cl^– secretion from both sides now. Schematic of
polarized autosomal-dominant polycystic kidney disease (ADPKD) cyst epithelial cell, depicting
transporters and signaling pathways involved in cyst Cl^– secretion. Cl^– secretion into the cyst
lumen (top) requires Cl^– entry into the cyst cell across its basolateral membrane via the Na⁺/
K⁺/2Cl^– cotransporter NKCC1, and Cl^– exit from the cyst cell across its apical membrane via protein
kinase A (PKA)-stimulated cystic fibrosis transmembrane conductance regulator (CFTR). Secretion
is under stimulatory control of cyclic AMP (cAMP) generated by the vasopressin-2 receptor (V2R),
modulated by the inhibitory somatostatin-2 receptor (SSTR2) and by stimulatory Ca²⁺-signaling
pathways involving phospholipase C-γ (PLCγ), inositol-triphosphate (IP₃), and other messengers. This
Cl^–-secretory process requires basolateral recycling of K⁺ via KCa3.1 and of Na⁺ via Na⁺, K⁺-ATPase.
Elevated cytosolic Ca²⁺ required for KCa3.1 activation can derive from endoplasmic reticulum (ER)
stores via ryanodine receptors (RyR), IP₃ receptors (IP₃R), and polycystin-2 (PC2). Activating Ca²⁺ can
also enter from extracellular fluid via transient receptor potential (TRP) channels, including PC2 in
complex with polycystin-1 (PC1) in the flow-sensitive monocilium (top), or in basolateral membrane,
store-operated channels (Orai) in complex with near-surface ER-localized Stim1, or via voltage-gated
Ca²⁺ channels (CaV). Cl^– secretion into the cyst lumen can be blocked at the basolateral membrane by
the KCa3.1 inhibitors senicapoc and TRAM-34 (ref. 3) (lower left) and at the apical membrane by CFTR
antagonists (upper right). Cl^- secretion can also be inhibited by V2R antagonists and somatostatin
analogues (lower right); PKA’s role in cAMP stimulation of cyst epithelial KCa3.1 is uncertain. Ca²⁺,
calcium ion; Cl^-, chloride ion; G_i, inhibitory G_α protein; G_s, stimulatory G_α protein; R, receptors for
various hormones; TJ, tight junction."

Эта объясняющая кое-что картинка взята из статьи Let's look at cysts from both sides now