Поссчитали еще в 2006 г. - Выгодно! Nephrol Dial Transplant (2006) 1 of 6
doi:10.1093/ndt/gfl606
Sodium citrate 4% locking solution for central venous dialysis catheters—an effective, more cost-efficient alternative to heparin
Results. During the study period, 30 925 and 37 139 catheter days were identified during the heparin and citrate years, respectively. The rate of flow-related
catheter exchange was not different during the two periods (1.81 vs 1.88 per 1000 catheter days, P¼0.89). Falsely elevated INR values were eliminated with citrate and the rate of rt-PA treatments was similar during the two periods (4.1 vs 3.23 per 1000 catheter days respectively, P¼0.07). The number of bacteraemias was similar during the two periods (0.77 vs 0.94 per 1000 catheter days respectively, P¼0.36) There was an 85% reduction in the costs associated with catheter-locking therapy during the citrate period.
Вот это экономия!
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В русском инете не совсем точный перевод здесь
Похожие данные в Clin J Am Soc Nephrol 3: 369-374, 2008 © 2008 American Society of Nephrologydoi: 10.2215/CJN.01760407
Citrate 4% versus Heparin and the Reduction of Thrombosis Study (CHARTS)
более свежие данные по этой теме за 2009 г
Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens)